Darin Tsui

Hi there! My name is Darin. I’m a Ph.D. student at the Georgia Institute of Technology studying Electrical and Computer Engineering and Bioengineering. I previously received my BS degree at the University of California San Diego in Bioengineering.
I currently work with Dr. Amirali Aghazadeh in the AI ML & Information Group, where I develop scalable, interpretable tools for generative models in the biosciences. I am currently supported by the NSF Graduate Research Fellowship. My research focuses on:
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Explaining black-box models by bridging the gap between interpretability and the sparse Fourier transform.
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Extracting higher-order interactions from models for scientific discovery.
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Developing principled generative models that leverage domain priors.
My background is highlighly interdisciplinary. I previously validated deep learning models at Surgalign (acquired by Xtant Medical), developed an optical surgical platform in the Talke Biomedical Device Lab, and designed a bioelectronic COVID-19 test in the Integrated Systems Neuroengineering Laboratory.
Outside of research, I co-chair Bioengineering Day at Georgia Tech, which aims to highlight interdisciplinary research . Previously, I served as President of the IEEE student branch and helped found the IEEE EMBS chapter at UC San Diego.
News
May 11, 2024 | I presented my work on uncovering higher-order interactions in protein language models at the ICLR Generative and Experimental Perspectives for Biomolecular Design (GEM) workshop. |
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Apr 04, 2024 | Excited to announce that I was awarded the National Science Foundation (NSF) Graduate Research Fellowship (GRFP) to support my PhD! |
Aug 31, 2023 | I had the opportunity to give a talk at the ASME Information Storage and Processing Systems (ISPS) on the promise of stereoscopic vision in computer-assisted surgery. |
Jul 31, 2023 | I had the opportunity to present my work at the IEEE Engineering in Medicine and Biology Society (EMBS) on machine learning COVID-19 detection and optical surgical navigation. |
Jun 23, 2023 | Happy to announce that I will be joining the Georgia Institute of Technology this Fall to pursue a Ph.D. in Electrical and Computer Engineering and Bioengineering! |
Selected Publications
- SHAP zero explains biological sequence models with near-zero marginal cost for future queriesarXiv preprint arXiv:2410.19236, 2025
- On recovering higher-order interactions from protein language modelsIn ICLR 2024 Workshop on Generative and Experimental Perspectives for Biomolecular Design (GEM) , 2024
- A low-cost, open-source-based optical surgical navigation system using stereoscopic visionMicrosystem Technologies, 2024